LOXO-292 demonstrates promising anti-tumor activity in RET-altered thyroid cancer

ITOG member Dr. Lori Wirth recently presented progress on a Phase 1/2 study of LOXO-292 at the European Society for Medical Oncology (ESMO) Annual Congress in Barcelona, Spain. This is an open-label, first-in-human study designed to evaluate the safety, tolerability, pharmacokinetics and preliminary anti-tumor activity of LOXO-292 administered orally to patients with advanced solid tumors, including RET-fusion-positive solid tumors, medullary thyroid cancer (MTC) and other tumors with RET activation.

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